mediastinitis sternum infection
Conditions
Interventions
Vacuum-Assisted Closure versus Closed Drainage using Redon Catheters .
Sponsors
cardioth chir
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: All patients that developed mediastinitis after cardiac surgery that need re-sternotomy and fulfill the criteria of mediastinitis according to the guidelines of the US Centers for Disease Control and Prevention (CDC): (1) an organism was isolated from culture of mediastinal tissue or fluid (2) evidence of mediastinitis was seen during the operation (3) one of the following conditions, chest pain, sternal instability, or fever (> 38) was present and there was either purulent discharge from the mediastinum or an organism isolated from blood culture or culture of drainage of the mediastinal area.
Exclusion criteria
Exclusion criteria: Patients who are mentally not able to chose whether to be involved in the study or not.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| · 2 en 5-year survival (Kaplan Meier analysis) · Quality of life (QLQ-C30 en C13) · Duration of wound healing (termination VAC therapy, removal of redon drains) · Freedom from mediastinal microbiological cultures · Freedom from re-intervention · CRP · Failure of treatment. | — |
Primary
| Measure | Time frame |
|---|---|
| .Primary: to compare discharge after vacuum-assisted drainage or redon drainage. | — |
Countries
Netherlands
Outcome results
None listed