individueel setpoint Hypothalamus Hypofyse Gonade as bij de man; een pilotstudy

individueel setpoint Hypothalamus Hypofyse Gonade as bij de man; een pilotstudy - individual setpoint hypothalamus pituitary gonad axis in men, a pilotstudy

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON30596

Enrollment

Registered

2007-07-23

Start date

2007-02-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

androgen deficiency hypogonadism

Interventions

ketoconazole 4 times 100 mg daily for 9 days. human chorionic gonadotropin 5000 IE once.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: male, age 18-40 years, healthy

Exclusion criteria

Exclusion criteria: intolerability of ketoconazole, use of testosterone, aldactone, finasteride, estradiol. Elevated liver enzymes, hypogonadism (T 8 IU/l), elevated estradiol level (>250 pmol/l)

Design outcomes

Primary

Measure	Time frame
levels of total testosterone and 17-OH-progesterone before and during ketoconazole use and after application of human chorionic gonadotropin	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)