Pain sensitivity in children and adults with Down syndrome: do they have altered pain thresholds and tolerance?

Pain sensitivity in children and adults with Down syndrome: do they have altered pain thresholds and tolerance? - Pain sensitivity in children with Down syndrome

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON30552

Enrollment

Registered

2007-07-31

Start date

2006-12-01

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

verstandelijk handicap Down syndrome and pain sensitivity

Interventions

All study subjects will undergo thermal (pain) stimuli.

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: Index group: Trisomy 21, (biological age 10-12 and 20-22 year-old). Both groups have a social and communicative adaptation behaviour corresponding with that of children without CI of >=7 years, i.e. total score on the Vineland-Z social domain >=97 and a total score on the Vineland-Z communication domain >=93 Reference subjects: children with a biological age of 7-12 years and young adults with a biological age of 20-22 years.

Exclusion criteria

Exclusion criteria: Index group: not able to tell what pain is and when they suffered pain, not responsible to reproduce the instructions given for testing, any record of behavioural or language problems, or use of anti-epileptics, anti-depressives, or spasmolytics. Reference groups: mental handicap, or use of anti-epileptics, anti-depressives, or spasmolytics.

Design outcomes

Primary

Measure	Time frame
Detection threshold warm, pain threshold heat pain, pain report to different heat and heat (pain) stimuli.	—

Secondary

Measure	Time frame
none	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)