Home treatment of patients with pulmonary embolism based on pro-BNP levels

Home treatment of patients with pulmonary embolism based on pro-BNP levels - HOME-study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30496

Enrollment

150

Registered

2006-08-03

Start date

2006-09-21

Completion date

Unknown

Last updated

2024-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pulmonary embolism

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1.outpatients with a pulmonary embolism, confirmed by locally approved guidelines 2.patients aged 18 years and above 3.written informed consent

Exclusion criteria

Exclusion criteria: 1.hemodynamic or respiratory instability, defined as one of the following symptoms: collapse, hypotension (RR systolic

Design outcomes

Primary

Measure	Time frame
To study the mortality rate due to pulmonary embolism or its treatment during a period of 10-days in patients with a normal pro-BNP concentration who are treated at home.	—

Secondary

Measure	Time frame
To study the rate of re-admission to hospital due to pulmonary embolism or his treatment (like a, b or c) during a period of ten days in the outpatient group. a. hemodynamic instability b. major bleeding c. recurrence of VTE o study the correlation between pro-BNP and: a. VQ-score b. Clinical score according to Wells To study the well being of patients treated at home, measured by the HADS anxiety score and the Patient satisfaction questionnaire PSQ-18. To study the course of pro-BNP in patients treated in hospital. We will also follow the group of patients treated in hospital to measure daily the pro-BNP levels and to correlate this with the clinical course. Probably is will be possible in future to send off home a patient, based on a clinical score and a normalized pro-BNP.	—

Measure

Time frame

To study the rate of re-admission to hospital due to pulmonary embolism or his treatment (like a, b or c) during a period of ten days in the outpatient group. a. hemodynamic instability b. major bleeding c. recurrence of VTE o study the correlation between pro-BNP and: a. VQ-score b. Clinical score according to Wells To study the well being of patients treated at home, measured by the HADS anxiety score and the Patient satisfaction questionnaire PSQ-18. To study the course of pro-BNP in patients treated in hospital. We will also follow the group of patients treated in hospital to measure daily the pro-BNP levels and to correlate this with the clinical course. Probably is will be possible in future to send off home a patient, based on a clinical score and a normalized pro-BNP.

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Countries

Netherlands

Outcome results