Towards a non-invasive anatomical and functional diagnostic work-up of patients with suspected coronary artery disease using Cardiovascular Magnetic Resonance Imaging and Multidetector CT

Towards a non-invasive anatomical and functional diagnostic work-up of patients with suspected coronary artery disease using Cardiovascular Magnetic Resonance Imaging and Multidetector CT - MARCC (MRI an CT in suspected coronary artery disease)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30468

Enrollment

220

Registered

2007-09-18

Start date

2007-09-10

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: VUMC CMR/MDCT work-up because of suspected coronary artery disease (CAD). Chest pain of intermediate likelihood for significant CAD as determined from age, gender and history (10-90% according to combined Diamond/Forrester/CASS scale; ref: Gibbons RJ et al. Circ 2003;107:149-158.). No prior documented CAD.

Exclusion criteria

Exclusion criteria: Any change in clinical condition between the examinations, failure to sign the informed consent.

Design outcomes

Primary

Measure	Time frame
Diagnostic accuracy of CMR, MDCT calcium score and MDCT coronary angiography for the detection of significant CAD, using invasive coronary angiography as reference standard. Development of a diagnostic algorithm (decision tree model) involving the sequential use of both imaging modalities.	—

Secondary

Measure	Time frame
Costs relative to diagnostic accuracy for CMR and MDCT, and for the proposed algorithm. One-year clinical outcome.	—

Countries

Netherlands

Outcome results