tandheelkundige slijmvlies aandoeningen Metal allergy
Conditions
Interventions
None listed
Sponsors
Universiteit van Amsterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients (>18 year) where the anamnesis gives rise to a suspicion of a metal allergy based on an oral exposure and where intra-oral inspection showed one of the following symptoms: 1) not plaque related mucosa deviation (e.g. gingivitis, periodontitis), 2) Lichenoid reaction, 3) Lingua geographica, 4) Local erosion, 5) Edema, 6) Erythema.
Exclusion criteria
Exclusion criteria: Patients/volunteers where the anamnesis showed malignancies and/or systemic diseases, or other disorders that hinder the execution of in vivo or in vitro allergy testing. ;Patients/volunteers who are pregnant.;The use of drugs that interferes with in vivo and/or in vitro allergic diagnostic tests.;Patients not willing to undergo the general diagnostic examination as normally offered by the department of Dermato-Allergy (VUmc) or the department of Oral Diagnostics (ACTA).;Patients of the negative control group were not positive patch tested before and should not have a history of eczema.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Determination of correlation coefficients between test results of four selected tests mutually as well as in relation with the diagnostic image of metal allergiy linked to an oral exposure to dental alloys. | — |
Countries
Netherlands
Outcome results
None listed