CVD cardiovascular disease
Conditions
Interventions
None listed
Sponsors
Jan van Breemen Instituut
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Patients with AS (according to the modified New York criteria); - aged 50 years and older; - registered at the Jan van Breemen Institute and/or the VU university medical center.
Exclusion criteria
Exclusion criteria: none
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CVD will be defined as an objectified history of coronary, cerebral or peripheral arterial disease. Coronary diseases will be defined as having a history of myocardial infarction, surgery for ischemic heart disease. Cerebrovascular disease is defined as a history of a transient ischemic attack, a stroke, or a carotid endarterectomy. Peripheral arterial disease will be defined as an aneurysm of the aorta abdominalis, peripheral arterial reconstructive surgery, limb amputation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic data: age, gender, disease duration, disease onset, co-morbidity, radiographic damage, medical history, medication history, family history. AS disease activity: Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), Bath Ankylosing Spondylitis Metrology Index (BASMI), Maastricht Ankylosing Spondylitis Enthesis Score (MASES), Ankylosing Spondylitis (Asqol) scores, history of orthopedic surgery, (history of) extra-articular manifestations. Cardiovascular risk factors: smoking, family history of premature CVD, (history of) hypertension, (history of) dyslipidemia, (history of) thyroid gland failure, and diabetes mellitus. Physical examination: blood pressure, pulse, height, length, body mass index (BMI), waist circumference, hip circumference, waist hip ratio (WHI), ankle branchial pressure index, EKG. Laboratory: Erythrocyte sedimentation rate (ESR), C-reactive protein, glucose (fasting), HbA1c, platelet counts, creatinine, thyroid stimulating hormone (TSH), lipids (total cholesterol, HDL, TG, Apo-A, Apo-B). | — |
Countries
Netherlands
Outcome results
None listed