Central sensitization of chronic pain and itch: generalized and symptom-specific mechanisms.

Central sensitization of chronic pain and itch: generalized and symptom-specific mechanisms. - Central sensitization of chronic pain and itch.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30317

Enrollment

384

Registered

2007-06-12

Start date

2006-11-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

atopic eczema fibromyalgia pruritis sine materia Rheumatoid arthritis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Diagnosis of rheumatoid arthritis, atopic eczema, fibromyalgia or pruritis sine materia Age of 18 years and older Informed consent Female gender

Exclusion criteria

Exclusion criteria: Severe physical and psychiatric comorbidity Double diagnoses with regard to the conditions investigated Pacemaker use Pregnancy

Design outcomes

Primary

Measure	Time frame
The sensitivity for the different somatosensory stimuli is determined by measuring the thresholds of perception, pain and tolerance with in addition the symptom report by a 0 to 10 scale for itch and pain.	—

Secondary

Measure	Time frame
To control for the induced psychological stress, measures of autonomic arousal (heart rate variability, skin conductance and electromyografy) are additionally assessed during one experiment.	—

Countries

Netherlands

Outcome results