gluten enteropathy gluten intolerance
Conditions
Interventions
The Dutch Coeliac Society (NCV) will invite to participate their members with
CD expecting a newborn (child or sibling) during the next months. Informed
consent to participate will be asked from the
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
2 Years to 11 Years
Inclusion criteria
Inclusion criteria: 1. Infant born during the study with a first degree relative (parent or sibling) with Coeliac Disease. 2. Family know by the NCV (Dutch coeliac disease association) 3. Informed consent for the study
Exclusion criteria
Exclusion criteria: 1. No informed consent for the study 2. Insufficient knowledge of the Dutch language. Parents-guardians unable to understand the information necessary to give informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In the European project (1000 children), reduction of 50% of CD development in the intervention group at the age of 3 years (25 children with CD, expected 50). | — |
Secondary
| Measure | Time frame |
|---|---|
| - Understanding of the influence of early nutrition on the development of CD in relation to immunologic and genetic factors. - If our strategy to develop tolerance for gluten happens to be effective: contribution to the development of new (evidence based) European guidelines for early infant feeding practices, aimed at the primary prevention of CD and related autoimmune diseases. | — |
Countries
Netherlands
Outcome results
None listed