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GH receptor polymorfism: the effects on growth hormone substitution in patients with growth hormone deficiency

GH receptor polymorfism: the effects on growth hormone substitution in patients with growth hormone deficiency - GH receptor polymorfisms in adult GHD

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON30312
Enrollment
200
Registered
2007-01-26
Start date
2006-11-01
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

growth hormone deficiency

Interventions

None listed

Sponsors

Leids Universitair Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Informed consent - All patients with growth hormone deficiency who have been treated with growth hormone substitution for at least one year

Exclusion criteria

Exclusion criteria: - Known pathogenic mutations in the growth hormone receptor that caused growth hormone deficiency.

Design outcomes

Primary

MeasureTime frame
1. The prevalence of the GH receptor polymorfisms. 2. The interactions of efficacy of GH substitution with GH receptor polymorfisms.

Secondary

MeasureTime frame
Not applicable.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)