Non-invasive prenatal diagnosis with PAP-assay; detection of cell free fetal DNA in maternal blood.

Non-invasive prenatal diagnosis with PAP-assay; detection of cell free fetal DNA in maternal blood. - Non-invasive prenatal diagnosis with PAP-assay

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30308

Enrollment

Registered

2008-04-17

Start date

2007-01-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

birth defect genetic defect

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Singleton pregnancy with gestational age between 9-16 weeks

Exclusion criteria

Exclusion criteria: multiple pregnancy, language restriction with failure to understand the study information.

Design outcomes

Secondary

Measure	Time frame
complications	—

Primary

Measure	Time frame
We will compare the results from the PAP-test in group 1, predicting the presence or absence of the fetal Y-gene with the karyotype results from the amniocentesis or chorionic villus sampling. The results from the PAP-test for the fetal Rh-D gene in group 2 will be compared with the results of Rh-typing from umbilical cord blood, routinely after delivery.	—

Countries

Netherlands

Outcome results