None listed
Conditions
Interventions
None listed
Sponsors
Universiteit van Tilburg
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients: Systolic heart failure; LVEF
Exclusion criteria
Exclusion criteria: Patients: Age >80 years; myocardial infarction during the month of inclusion; other life-threatening diseases; clinical signs of acute infection; co-morbid chronic inflammatory or auto-immune disease (e.g. Rheumatoid Arthritis); use of substantial anti-inflammatory medication (e.g. cortisol); evident cognitive impairments; chronic severe psychiatric condition (e.g. psychosis).;Partners: Evident cognitive impairments; chronic severe psychiatric condition (e.g. psychosis).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Personality (Type D and hostility) and mood are independent predictive variables. Mediating variables are immunoparameters and psychological variables (self-management and loneliness). Moderators are medical on the one hand (NYHA class, etiology), and psychological on the other hand (positive affectivity, sense of coherence and marital satisfaction). Primairy outcomes are defined as quality of life, health care utilization, and the combined endpoint of mortality and rehospitalizations. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secundary endpoint is defined as cardiac mortality. | — |
Countries
Netherlands
Outcome results
None listed