The use of narrow band imaging versus conventional colonoscopy for the detection of dysplasia and cancer in patients with longstanding ulcerative colitis. A randomized cross-over study

The use of narrow band imaging versus conventional colonoscopy for the detection of dysplasia and cancer in patients with longstanding ulcerative colitis. A randomized cross-over study - EVE II study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30287

Enrollment

Registered

2007-01-04

Start date

2007-01-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inflammatory bowel disease ulcerative colitis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: objective diagnosis (endoscopically and histologically proven) of ulcerative colitis extensive colitis (defined as inflammation proximal to the splenic flexure) disease history longer than 8 years inactive disease

Exclusion criteria

Exclusion criteria: non correctable coagulopathy age younger than 18 years inability to give informed consent

Design outcomes

Primary

Measure	Time frame
The sensitivity of NBI will be compared to WLE in terms of the number of patients with detected neoplasia.	—

Secondary

Measure	Time frame
- In addition, the number of detected neoplastic lesions will be compared between both techniques. - Moreover, Kudo*s classification, mucosal morphology and vascular patterns (imaged by NBI) will be evaluated for their ability to distinguish neoplastic and non neoplastic lesions.	—

Countries

Netherlands

Outcome results