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Is there an improvement of microcirculation regarding propofol vs. sevoflurane anaesthetic regimen during coronary artery bypass grafting?

Is there an improvement of microcirculation regarding propofol vs. sevoflurane anaesthetic regimen during coronary artery bypass grafting? - SEVOMICAB

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON30260
Enrollment
50
Registered
2007-04-13
Start date
Unknown
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary artery disease occlusive vascular disease

Interventions

None listed

Sponsors

Anesthesiologie
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: All patients undergoing elective CABG are included.

Exclusion criteria

Exclusion criteria: Exclusion criteria includes emergency surgery, recent myocardial infarction (less than 7 days old), concurrent valve surgery or redo CABG, chronic use of either corticosteroid medication or NSAIDS.

Design outcomes

Primary

MeasureTime frame
5.1 Endpoints: 5.1.1) Myocardial cell damage markers (Troponin I, CK, CK-MB) between both groups on T(0) to T(7). See protocol for Time intervals (T)—

Secondary

MeasureTime frame
5.1.2) Hemodynamic data, for example CO, CI, SV, SVR, PVR on T (0) to T(3). 5.1.3) Microcirculation as measured by MFI on T(0) to T(5). 5.1.4) Inflammatory markers (for example: leucocytes, CRP, TNF-a, IL-6, CD11b/CD18 cells).—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)