Pressure and Silicone treatment in Hypertrophic Scarring

Pressure and Silicone treatment in Hypertrophic Scarring - Hypertrophic Scarring

Status

Active, not recruiting

Phases

Phase 3

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30255

Enrollment

Registered

2006-11-09

Start date

2007-01-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

burn scars Hypertrophic scarring

Interventions

The intervention consist of the application of pressure with or without silicone inlays on the hypertrophic scars.

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Only patients with an objectified developing hypertrophy as measured by colorimetry will be included. An erythema value of 140% of normal healthy skin is required. - All scars younger than 6 months post-woundclosure can be included

Exclusion criteria

Exclusion criteria: - Age 65yrs - Preëxistent skin disease -Degenerative or metabolic disorders (use of immunosupressives, immuno

Design outcomes

Secondary

Measure	Time frame
Concentrations of TGFbeta 1, 2 and 3 and MMP 9 The histological findings will also be correlated to the clinical differences in erythema and thickness.	—

Primary

Measure	Time frame
Apoptosisrate of fibroblasts	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)