Influence of the donor-host interface on results of keratoplastic procedures currently in use in corneal surgery. A structured follow-up.

Influence of the donor-host interface on results of keratoplastic procedures currently in use in corneal surgery. A structured follow-up. - Structured follow-up of keratoplasty.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30230

Enrollment

210

Registered

2006-12-04

Start date

2007-03-19

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

corneal transplant

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Group 1, PKP: - BCVA >= 0.4 (logMAR) - not eligible for ALTK, DALK, PLK;Group 2, ALTK: - BCVA >= 0.4 (logMAR);Group 3, DALK: - BCVA >= 0.4 (logMAR) - keratoconus without hydrops or Descemet*s rupture - stromal opacities not reaching Descemet*s membrane - no concommitant endothelial disease;Group 4, PLK: - BCVA >= 0.4 (logMAR) - endothelial dysfunction caused by pseudophakic or aphakic edema - (Fuch*s) endothelial dystrophy

Exclusion criteria

Exclusion criteria: Group 1, PKP: - mental retardation - previous corneal surgery ;Group 2, ALTK: - mental retardation - history of (penetrating) keratoplasty - HLA-typed keratoplasty;Group 3, DALK: - mental retardation - history of (penetrating) keratoplasty - HLA-typed keratoplasty;Group 4, PLK: - mental retardation - history of (penetrating) keratoplasty - HLA-typed keratoplasty - severe scarring of anterior stroma

Design outcomes

Primary

Measure	Time frame
Quantification of possible relationship between corneal reflectivity (confocal microscopy) and: - visual acuity (logMAR) - contrast sensitivity (Pelli Robson chart) - keratoplastic technique	—

Secondary

Measure	Time frame
Quantification of possible relationship between corneal reflectivity and: - scatter measured by Oculus C-quant - pachymetry (3 methods) Quantification of: - endothelial cell density - quality of life	—

Countries

Netherlands

Outcome results