Effect of aging on metabolism and on clinical outcome after colorectal surgery. Assessment of preoperative riskfactors on postoperative morbidity and mortality.

Effect of aging on metabolism and on clinical outcome after colorectal surgery. Assessment of preoperative riskfactors on postoperative morbidity and mortality. - Aging

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30212

Enrollment

100

Registered

2006-12-13

Start date

2007-09-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aging elderly patient

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Admission for elective abdominal surgery for colon or rectal carcinoma. • Age: >55 years. • Fit for elective surgery as defined by ASA score. • Having obtained his/her informed consent

Exclusion criteria

Exclusion criteria: Younger than 55 years

Design outcomes

Primary

Measure	Time frame
Infectious complications (fever, pneumonia, sepsis, bacteraemia, intrathoracic or intra-abdominal infection, major wound infection, central-line infection, urinary-tract infection); non-infectious complications as CV-complications (infarct, cardiac failure, cerebrovascular accident, deep venous thrombosis, hypotension and infarct), re-operation, transfusion-needed anemia, anastomotic leakage and MOF; nutritional status by weight, BMI, Bioelectrical Impedance Analysis (LBM, skeletal body mass, ECF, ICF, TBW) and metabolic status by and amino acid profiles, CRP, albumin, glucose, insulin, fructosamine, HbA1c and ADMA.	—

Measure

Time frame

Infectious complications (fever, pneumonia, sepsis, bacteraemia, intrathoracic or intra-abdominal infection, major wound infection, central-line infection, urinary-tract infection); non-infectious complications as CV-complications (infarct, cardiac failure, cerebrovascular accident, deep venous thrombosis, hypotension and infarct), re-operation, transfusion-needed anemia, anastomotic leakage and MOF; nutritional status by weight, BMI, Bioelectrical Impedance Analysis (LBM, skeletal body mass, ECF, ICF, TBW) and metabolic status by and amino acid profiles, CRP, albumin, glucose, insulin, fructosamine, HbA1c and ADMA.

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Countries

Netherlands

Outcome results