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The putative role of keratoconjunctivitis sicca in the development of blepharoptosis.

The putative role of keratoconjunctivitis sicca in the development of blepharoptosis. - Dry eyes & ptosis.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON30204
Enrollment
200
Registered
2006-12-05
Start date
2007-04-02
Completion date
Unknown
Last updated
2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

drooping eye lid

Interventions

None listed

Sponsors

Oogziekenhuis Rotterdam
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Group 1 (ptosis): - Diagnosis of gradually developed unilateral or bilateral ptosis of the upper eye lid. - Age >= 40 years for patients not wearing contact lens(es) in affected eye(s). - Age >= 20 years for patients wearing contact lens(es) in affected eye(s). - Vertical eyelid fissure 10 mm.;Group 2 (no ptosis): - Age >= 40 years for patients not wearing contact lens(es). - Age >= 20 years for patients wearing contact lens(es). - Vertical eyelid fissure > 7 mm in primary position. - Bilateral levator function > 10 mm. - Age and gender match to a patient from group 1 ( |*age|

Exclusion criteria

Exclusion criteria: Group 1 (ptosis): - Neurological disorder. - Muscular disorder. - Suspicion of other possible cause.;Group 2 (no ptosis): - Neurological disorder. - Muscular disorder.

Design outcomes

Primary

MeasureTime frame
Significant difference in proportion of patients with dry eyes between groups (*2, a=0.05).

Secondary

MeasureTime frame
Schirmer-2 score, tear break-up time, corneal staining, degree of ptosis, record of possible risk factors (previous trauma, contact lens wear, ocular surgery, subjective complaints, punctate keratitis, blepharitis, etc.).

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)