Assessment of patients with PPI-refractory GORD: reflux monitoring with or without proton pump inhibitor?

Assessment of patients with PPI-refractory GORD: reflux monitoring with or without proton pump inhibitor? - Reflux monitoring: with or without PPI?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30183

Enrollment

Registered

2006-10-06

Start date

2006-10-26

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

heartburn

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: age > 18 years typical reflux symptoms (haertburn, regurgitation, chest pain) that do not repond satisfactorily to double dose PPI-therapy

Exclusion criteria

Exclusion criteria: surgery of stomach or oesophagus in patients history condition which contraindicates the cessation of PPI therapy such as peptic ulcer disease

Design outcomes

Primary

Measure	Time frame
Main study parameters/endpoints: For each reflux measurement the Symptom Association Probability is calculated. Both methods will be compared according to Bland-Altman analysis.	—

Secondary

Measure	Time frame
None	—

Countries

Netherlands

Outcome results