The variations in small vascular wall function during the menstrual cycle in young healthy women.

The variations in small vascular wall function during the menstrual cycle in young healthy women. - MCycle

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30179

Enrollment

Registered

2006-10-12

Start date

2006-10-01

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

het betreft geen aandoening er wordt gekeken naar de vaatfunctie in de cyclus van gezonde vrouwen nvt

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Healthy as judged by history and physical examination - Regular ovulatory menstrual cycles between 21- 35 days (proven by biphasic BTC or midluteal progesterone > 10 nmol/l) -18- 35 years - no medication including oral conceptive or hormonal intra- uterine device (IUD) for at least three months

Exclusion criteria

Exclusion criteria: - Cardiovascular disease (hypertension (>160/90 mmHg), stroke, coronary artery disease,peripheral vascular disease, heart failure) -Diabetes mellitus (according to ADA criteria ) -Smoking for the last three months -Alcohol use > 4U/day -Diseases that influence reproductive hormone status

Design outcomes

Primary

Measure	Time frame
- cycle dependent microvascular function - microvascular function is measured in three different ways: 1. capillary refill (with the microscope) 2. endothelial dependent and independent vasodilatation (iontophoresis) 3. insulin dependent vasodilation 4. vasomotion	—

Secondary

Measure	Time frame
nvt	—

Countries

Netherlands

Outcome results