parodontologie Bone loss in between two roots of a molar Furcation defect
Conditions
Interventions
Periodontal regenerative surgery. The furcation defects will be randomly
treated with a bovine derived xenograft (Tutodent® microchips [Tutogen,
Neunkirchen am Brand, Germany]) in combination with a
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Periodontitis patients, diagnosed with chronic periodontitis, having reached at least the first re-evaluation time point after the initial phase of periodontal therapy. All patients will have buccal class II furcation involvement in mandibular first or second molars.
Exclusion criteria
Exclusion criteria: Beside the threshold levels decided for FMPS (25%) and FMBS (25%), patients will not be included in this study, (1) if they are systemically not healthy (that is, having any systemic condition that precludes periodontal surgery, or that might compromise wound healing), (2) if not diagnosed with chronic periodontitis, (3) treated with antibiotics within 3 months prior to surgery, (4) current smokers, and (5) involved in any other clinical trial. On a site level, the selected lower first or second molars will have (1) mandibular buccal class II furcation involvement (HPD > 3 mm), (2) proximal bone levels at or above the fornix of the furcation, and (3) a zone of keratinized tissue of at least 2 mm adjacent to the furcation defect, in order to provide coverage of the furcation entrance during surgery. If, (4) a root canal treatment was performed, the selected tooth must be asymptomatic and the root canal treatment must be without technical remarks, and (5) such a root canal treatment must be completed at least six months before the selected tooth is enrolled in the study. Teeth will be excluded from the study, if (1) buccal restorations extend to the furcation area in a way that the margins of these restorations are less than 1 mm away from the entrance of the furcation, (2) they have in addition lingual class II furcation involvement (HPD > 3 mm), (3) they are non-vital and have posts or screw retentive devices, (4) they are non-vital and are not endodontically treated, (5) furcation class III involvement is revealed during surgery, or (6) they have enamel projections into the furcation defect not being removable during surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Efficacy of therapy will be described by change of horizontal probing bone level measurements (HPBL) as primary parameter. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters are full-mouth plaque scores (FMPS), full-mouth bleeding on probing scores (FMBS), site plaque score (SPS), site bleeding on probing score (SBS), probing pocket depth (PPD), clinical attachment level (CAL), recession (REC), horizontal probing depth (HPD), vertical probing bone level measurement (VPBL), vertical open bone level measurement (VOBL), and horizontal open bone level measurement (HOBL). | — |
Countries
Netherlands
Outcome results
None listed