Clinical parameters and biomarkers in blood and urine as predictors for bacteremia, hospital admission, morbidity and outcome in patients with complicated urinary tract infections. A study in primary care, the medicine emergency room and ICunit.

Clinical parameters and biomarkers in blood and urine as predictors for bacteremia, hospital admission, morbidity and outcome in patients with complicated urinary tract infections. A study in primary care, the medicine emergency room and ICunit. - Predictive value of biomarkers in complicated urinary tract infection.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30099

Enrollment

600

Registered

2006-06-22

Start date

2006-09-11

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infection of kidney Pyelonephritis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - at least one symptom suggestive of urinary tract infection , and - fever, and - positive urine nitrate test or - positive leukocyte esterase test

Exclusion criteria

Exclusion criteria: - polycystic kidney disease - end-stage renal failure - renal transplant

Design outcomes

Secondary

Measure	Time frame
Course of microbiological and host-derived biomarkers in urine and serum, assessed by massspectrometry.	—

Primary

Measure	Time frame
Clinical cure (resolution of symptoms; determined by diary and follow up after one and three months) and microbiological cure (negative urine culture) after one month. Duration of fever, hospital and/or ICU stay, and outcome, both with respect to course of disease (fever days, development of circulatory shock, multiple organ dysfunction, need of stay in ICU stay and/or urological intervention, number of sick days) as well as recovery or death.	—

Measure

Time frame

Clinical cure (resolution of symptoms; determined by diary and follow up after one and three months) and microbiological cure (negative urine culture) after one month. Duration of fever, hospital and/or ICU stay, and outcome, both with respect to course of disease (fever days, development of circulatory shock, multiple organ dysfunction, need of stay in ICU stay and/or urological intervention, number of sick days) as well as recovery or death.

—

Countries

Netherlands

Outcome results