Identification of low allergenic apple cultivars and assessment of proper chain conditions in view of apple allergy

Identification of low allergenic apple cultivars and assessment of proper chain conditions in view of apple allergy - Low allergenic apple cultivars

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON30093

Enrollment

Registered

2006-09-12

Start date

2006-06-01

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

apple allergy oral allergy syndrome

Interventions

year 1: apple cultivars are tests by SPT (prick to prick) year 2: oral challenge tests using least allergenic apple cultivars as well as 1 allergenic cultivar. breeding germplasms tested by SPT (p

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: age 18 and above anamnestich oral allergy symptoms following eating fresh apple positive open food challenge with reference apple cultivar

Exclusion criteria

Exclusion criteria: absence of anamnestic oral allergy symptoms following eating fresh apple negative open challenge with reference appel cultivar generalised or systemic symptoms follwoing eatiing fresh aple pregnancy

Design outcomes

Primary

Measure	Time frame
Scoring of subjective symptoms of OAS on a VAS-scale by patients Scoring of objective symptoms, if occuring, on a symptom scale, grading 1 - 3, by the physician	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)