Cross-sectional study of the characteristics of arthropathy in long-term well-controlled acromegalic patients

Cross-sectional study of the characteristics of arthropathy in long-term well-controlled acromegalic patients - Arthropathy in acromegaly

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30077

Enrollment

200

Registered

2006-11-15

Start date

2007-10-15

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

joint problems in acromegaly (acromegalia)

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Informed consent. - All patients treated for acromegaly by surgery, radiotherapy and medical treatment and followed at the Dept of Endocrinology with control of disease activity defined as a normal IGF-I for age and/ or a normal glucose-induced GH suppression. - Appropriate hormonal substitution of dysfunctional hormonal axes.

Exclusion criteria

Exclusion criteria: - Pregnancy

Design outcomes

Primary

Measure	Time frame
-clinical parameters: extensive physical examination -radiological parameters: knee, hands, hip and axial skeleton -functional parameters: assessment of hand/ shoulder/ lower extremity function -biochemical parameters: parameters of hormonal status/ inflammation/ osteoarthritis -DNA: genes associated with predisposition of osteoarthritis and pituitary adenomas	—

Secondary

Measure	Time frame
N.A.	—

Countries

Netherlands

Outcome results