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The contribution of the central nervous system to fatigue in patients suffering from MS

The contribution of the central nervous system to fatigue in patients suffering from MS - Central fatigue in MS patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON30067
Enrollment
30
Registered
2006-10-30
Start date
2006-10-16
Completion date
Unknown
Last updated
2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MS multiple sclerosis white matter disease

Interventions

Subjects perform shortlasting contracties in the scanner followed by a fatiguing 3-minute contraction.

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients suffering from Multiple Sclerosis

Exclusion criteria

Exclusion criteria: neurological disorders other than MS, fMRI exclusion criteria (e.g. metal implants)

Design outcomes

Primary

MeasureTime frame
The EMG obtained during the experiment will be analysed with Brain Vision Analyser. The mean EMG values during a contraction is one of the main parameters Furthermore, force and brain activitity will be measured. The main focus of this experiment is the time course of the braina ctivity during the experiment and the correlation between EMG/force and brain activity.

Secondary

MeasureTime frame
none

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)