Correlation of White Matter Fractional Anisotropy Measurements at 3T MRI with Neurocognitive Function in Childhood Cancer Survivors: a Pilot Study

Correlation of White Matter Fractional Anisotropy Measurements at 3T MRI with Neurocognitive Function in Childhood Cancer Survivors: a Pilot Study - White matter MRI and cognitive outcome childhood cancer survivors

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30064

Enrollment

Registered

2007-01-04

Start date

2006-09-15

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

brain damage after childhood cancer

Interventions

None listed

Eligibility

Age

2 Years to 17 Years

Inclusion criteria

Inclusion criteria: - Age and sex matched control between 8-16 years selected from the classmates of the patient with an average cognitive performance

Exclusion criteria

Exclusion criteria: 1. Psychological contraindications for MR Imaging are claustrophobia and / or need for sedation to perform MRI successfully.. 2. Physical contraindication for MR Imaging metallic implants or metallic orthodontic material.

Design outcomes

Primary

Measure	Time frame
White matter fraction anisotropy as measured by MR. Neurocognitive functioning of children including IQ as measured with intelligence testing and questionaires.	—

Secondary

Measure	Time frame
The reason for refusal to participate will be registered in order to improve the design of future ongoing studies concerning brain imaging and neurocognitive outcome after childhood cancer.	—

Countries

Netherlands

Outcome results