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Impaired regulation of Toll-like receptor-2 mediated T helper type 1 responses in NOD2/CARD15 deficient Crohn*s disease patients

Impaired regulation of Toll-like receptor-2 mediated T helper type 1 responses in NOD2/CARD15 deficient Crohn*s disease patients - Regulation of TLR-responses

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON30051
Enrollment
20
Registered
2006-04-28
Start date
2006-03-15
Completion date
Unknown
Last updated
2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Vrije Universiteit Medisch Centrum
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patient with Crohn's disease at least 18 years of age known NOD2/CARD15 genotype

Exclusion criteria

Exclusion criteria: severe anaemia

Design outcomes

Primary

MeasureTime frame
Levels of cytokine production, mRNA expression and NFkB activation as a response to stimulation with the different stimuli.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)