A genetic study of left-handedness and language lateralization in extended pedigrees from a Dutch population isolate. An investigation of a possible endophenotype for psychosis

A genetic study of left-handedness and language lateralization in extended pedigrees from a Dutch population isolate. An investigation of a possible endophenotype for psychosis - lateralisation and left handedness

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON30043

Enrollment

600

Registered

2006-06-27

Start date

2006-09-25

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

decreased lateralization left-handedness

Interventions

None listed

Eligibility

Age

12 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. All grandparents born in the Netherlands 2. Age minimal 14 years 3. left handed or right handed within a family with 3 or more left handed members.

Exclusion criteria

Exclusion criteria: 1. age below 14 years 2. less than 3 left handed family members 3. not all grandparents born in the Netherlands

Design outcomes

Primary

Measure	Time frame
1) co-segegration of left-handedness and decreased language lateralization 2) association of genomic candidate regions with left-handedness and decreased language lateralization 3) the association of identified candidate genes or genomic regions with left-handedness in an existing sample of schizophrenia patients and their association with schizophrenia in a case-control design.	—

Countries

Netherlands

Outcome results