High pressure in the bloodvessels of the lungs
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Mean pulmonary artery pressure (mPAP) > 25 mmHg - Stable on therapy for at least 3 months - Idiopathic pulmonary arterial hypertension
Exclusion criteria
Exclusion criteria: - Presence of systemic inflammation - Patients with pulmonary hypertension associated with collagen vascular disease, congenital heart disease, chronic thrombo-embolic pulmonary hypertension, pulmonary venous hypertension, left heart failure, hypoxemic lung disease - Patients with musculoskeletal problems prohibiting maximal exercise performance
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameters: - Change in strength and endurance of the quadriceps muscles - Change in exercise tolerance - Change in biochemical and morphological characteristics of the quadriceps muscles | — |
Countries
Netherlands