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Molecular mechanisms in the host-pathogen interaction in neonates; an approach on the level of gene and protein expression

Molecular mechanisms in the host-pathogen interaction in neonates; an approach on the level of gene and protein expression - Gene and protein expression in neonates with staphylococcal sepsis

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON30013
Enrollment
10
Registered
2006-11-23
Start date
Unknown
Completion date
Unknown
Last updated
2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

blood stream infection

Interventions

None listed

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
2 Years to 11 Years

Inclusion criteria

Inclusion criteria: Admission on neonatal intensive care unit Clinical signs of late-onset sepsis Weight at least 750 g

Exclusion criteria

Exclusion criteria: Birth weight

Design outcomes

Primary

MeasureTime frame
Difference in genomic transcription profiles and protein profiles between patients and controls.

Secondary

MeasureTime frame
To gain insight in similarities and differences in gene expression profiles between neonates suffering from CoNS sepsis and children suffering from meningococcal sepsis.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)