Neonatal thymectomy; consequences for homeostasis and regulation of the immune system?

Neonatal thymectomy; consequences for homeostasis and regulation of the immune system? - Impact of thymectomy on the immune system

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON29974

Enrollment

100

Registered

2007-01-02

Start date

2008-01-25

Completion date

Unknown

Last updated

2024-08-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

congenital heartdisease transposition of the great arteries

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: Arterial switch operation in the Wilhelmina Kinderziekenhuis between 1977 and 2003

Exclusion criteria

Exclusion criteria: moved abroad

Design outcomes

Primary

Measure	Time frame
1) Number of FOXP3+ cells compared to healthy controls 2) Ratio naïve T cells : memory T cells 3) Proliferate rate of naïve and memory T cell pool	—

Secondary

Measure	Time frame
1) Incidence of autoimmune diseases, malignancies, infectiousdiseases	—

Countries

Netherlands

Outcome results