epilepsy
Conditions
Interventions
None listed
Sponsors
Stichting Epilepsie Instellingen Nederland (SEIN)
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: General inclusion criteria 1. Adult patients with cryptogenic or symptomatic localization-related epilepsy, manifesting in generalized tonic-clonic, complex partial and/or simple partial seizures. 2. Patients that are able to understand the written information about the study and are able to give informed consent.
Exclusion criteria
Exclusion criteria: Exclusion criteria: 1. Patients failing valproate due to other reasons than persisting seizures despite a maximum tolerated dose (i.e. failure due to adverse effects on a starting dose of valproate, failure due to non-compliance etc). 2. Patients with generalized epilepsy and/or generalized absence-seizures and /or myoclonic seizures. 3. Acute or progressive neurological disease. 4. History of psychiatric disease or substance addiction.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presence of selected polymorphisms in the three patient groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of antiepileptic drugs used; epilepsy subtype; seizure type. | — |
Countries
Netherlands
Outcome results
None listed