Role of the cholesteryl ester transfer protein (CETP) in retinoid-associated dyslipidemias in patients treated for cuteanous disorders.

Role of the cholesteryl ester transfer protein (CETP) in retinoid-associated dyslipidemias in patients treated for cuteanous disorders. - CETP/retinoids

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON29950

Enrollment

Registered

2006-11-14

Start date

2006-09-01

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dyslipidemia hypoHDLemia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: People suffering from severe forms of acne or psoriasis requiring a treatment with Roaccutane or Neotigason, but who did not start with the treatment yet.

Exclusion criteria

Exclusion criteria: Treatment with hypolipidemic or antidiabetic drugs. Hepatic disorders Alcoholism Diabetes Acute infection

Design outcomes

Primary

Measure	Time frame
- CETP activity : fluorescent kinetics in microplates - Plasma CETP concentration : enyme-linked immunosorbent assay (ELISA)	—

Secondary

Measure	Time frame
- Plasma lipid levels (cholesterol, phospholipids, triglycerides): enzymatic assays - Cholesterol and triglyceride distribution between lipoprotein classes, and HDL size : fast protein liquid chromatography (FPLC) non-denaturing electrophoresis.	—

Countries

Netherlands

Outcome results