chronic pancreatitis
Conditions
Interventions
Intragastric and intrajejunal tube feeding.
Sponsors
Universitair Medisch Centrum Sint Radboud
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: · Pain is aggravated by meal ingestion, at least 3 times per week in past month · Pain most likely due to chronic pancreatitis (CP) · Pain is daily (type B-pain) · Pain is stable for more than 3 months · Clinical indication for enteral feeding · Diagnosis of chronic pancreatitis · Age > 18 y;
Exclusion criteria
Exclusion criteria: · Intermittent pain with pain free days (type A pain) · Exocrine pancreatic insufficiency · Duodenal or choledochal stenosis · Narcotic analgesics except tramadol · Surgery of stomach, pancreas, duodenum or jejunum · Jejunostomy for enteral feeding · Instable pain medication · No abstinence from alcohol in alcoholic CP · Evidence that abdominal pain may not be related to feeding or may not originate from pancreas · Other disorders of the upper gastrointestinal tract · Liver or biliary disorders . Contra-indication for enteral tube placement . Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intensity of abdominal pain | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters of the study are severity of other abdominal symptoms, health related quality of life, global releave score, global evaluation of efficacy score, concentrations of circulating gut hormones. | — |
Countries
Netherlands
Outcome results
None listed