slaapstoornissen sleeping disorders in attention deficit hyperactivity disorder
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Patients undergoing diagnostic assesment for ADHD at PsyQ Programme Adult ADHD; - The diagnosis of ADHD is made based on the usual diagnostic procedures: Semi-structured interview for adult ADHD; ADHD-Rating Scale (questionnaire on attentiondeficit and hyperactivity); - Subjects are aged 18 - 55 years; - Subjects are able to read and understand informed consent forms; - Subjects are willing and able to answer the research questionnaires and commit to appointments concerning the study.
Exclusion criteria
Exclusion criteria: - Comorbid axis-1 disorders which are clearly present at diagnostic assesment and which can interfere with either the patient's benefit and importance of proper treatment, or the study objectives: o psychotic disorder; o major depressive disorder; o anxiety disorder; o severe current substance abuse / dependence: more than 2 units of alcohol/day, or in females more than 15 units/wk, in males 21 units/wk; cannabis: more than 1 joint/day. Use of harddrugs is an exclusion criterium; -Presence of disorders described above will be assessed during the usual diagnostic procedure, and when necessary rigorous psychiatric evaluation will be carried out; - Use of the following medication within 1 month before participation: stimulants, antidepressants, melatonin, antipsychotics (neuroleptics), clonidine, benzodiazepines (hypnotics), bèta-blockers; - Suspected dementia, amnestic disorder or other cognitive disorder (DSM-IV); - Mental retardation; - Insufficient knowledge of Dutch language; - Shift work (evening or night) or travelling along > 2 time zones in the last two weeks.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Between groups with and without sleep onset disorders the following results will be compared: - sleep parameters (time to bed, sleep onset SO, sleep latency, wake-up time WT, get-up time, total sleep duration); - time of salivary melatonin production onset (Dim Light Melatonin Onset); - phase angles between DLMO-SO and DLMO-WT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Between groups with and without sleep onset disorders the following results will be compared: - melatonin concentration in total amount of overnight urinary production; - results of questionnaires concerning other sleep disorders, sleep hygiëne, and additional chronobiological and general health variables; - non-parametric actometric variables to evaluate (the variability in) rest-activity patterns. | — |
Countries
Netherlands