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Are sleep onset problems in adults with ADHD related to a disruption of the circadian rhythm?

Are sleep onset problems in adults with ADHD related to a disruption of the circadian rhythm? - Sleep problems in ADHD

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON29883
Enrollment
40
Registered
2006-06-13
Start date
2006-07-01
Completion date
Unknown
Last updated
2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

slaapstoornissen sleeping disorders in attention deficit hyperactivity disorder

Interventions

None listed

Sponsors

Parnassia (Den Haag)
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Patients undergoing diagnostic assesment for ADHD at PsyQ Programme Adult ADHD; - The diagnosis of ADHD is made based on the usual diagnostic procedures: Semi-structured interview for adult ADHD; ADHD-Rating Scale (questionnaire on attentiondeficit and hyperactivity); - Subjects are aged 18 - 55 years; - Subjects are able to read and understand informed consent forms; - Subjects are willing and able to answer the research questionnaires and commit to appointments concerning the study.

Exclusion criteria

Exclusion criteria: - Comorbid axis-1 disorders which are clearly present at diagnostic assesment and which can interfere with either the patient's benefit and importance of proper treatment, or the study objectives: o psychotic disorder; o major depressive disorder; o anxiety disorder; o severe current substance abuse / dependence: more than 2 units of alcohol/day, or in females more than 15 units/wk, in males 21 units/wk; cannabis: more than 1 joint/day. Use of harddrugs is an exclusion criterium; -Presence of disorders described above will be assessed during the usual diagnostic procedure, and when necessary rigorous psychiatric evaluation will be carried out; - Use of the following medication within 1 month before participation: stimulants, antidepressants, melatonin, antipsychotics (neuroleptics), clonidine, benzodiazepines (hypnotics), bèta-blockers; - Suspected dementia, amnestic disorder or other cognitive disorder (DSM-IV); - Mental retardation; - Insufficient knowledge of Dutch language; - Shift work (evening or night) or travelling along > 2 time zones in the last two weeks.

Design outcomes

Primary

MeasureTime frame
Between groups with and without sleep onset disorders the following results will be compared: - sleep parameters (time to bed, sleep onset SO, sleep latency, wake-up time WT, get-up time, total sleep duration); - time of salivary melatonin production onset (Dim Light Melatonin Onset); - phase angles between DLMO-SO and DLMO-WT;

Secondary

MeasureTime frame
Between groups with and without sleep onset disorders the following results will be compared: - melatonin concentration in total amount of overnight urinary production; - results of questionnaires concerning other sleep disorders, sleep hygiëne, and additional chronobiological and general health variables; - non-parametric actometric variables to evaluate (the variability in) rest-activity patterns.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)