food allergy IgE mediated food allergy
Conditions
Interventions
Patients will be asked to undergo DBPCFC. They will intake lupine flour that is
hidden in small cookies. It may be possible that lupine flour is not a part of
the diet of the patient and in that cas
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients with a possible food allergy (complaints after intake of certain food) and a positieve skin test (HEP (Histamine Equivalent Prick test) index > 0.15) with lupine flour - and peanut extract. Older than 18 years
Exclusion criteria
Exclusion criteria: pregnancy, inability to stop anti histamines, using medication affecting provocation: e.g. prednison, cyclosporine, montelukast
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin tests with lupine flour, peanut and soy. Reactions on DBPCFC's. Presence of specific IgE against lupine flour in the serum of the patient. | — |
Secondary
| Measure | Time frame |
|---|---|
| Presence of cross - reacting allergenes. | — |
Countries
Netherlands
Outcome results
None listed