Genetic studies in patients with nonsyndromic orofacial clefts.

Genetic studies in patients with nonsyndromic orofacial clefts. - Genetics of orofacial cleft

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON29856

Enrollment

450

Registered

2007-02-13

Start date

2007-01-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cleft lip/palate orofacial cleft

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: patients with nonsyndromic orofacial clefts and their affected sibs parents of patients with nonsyndromic orofacial clefts only persons who originate from Central European countries will be included

Exclusion criteria

Exclusion criteria: patients with syndromal orofacial clefting patients from countries outside of Central Europe

Design outcomes

Primary

Measure	Time frame
For the researchers from Nijmegen the primary goal is to collect bloodsamples of patients with cleft lip/palate and their parents.	—

Secondary

Measure	Time frame
In Bonn analyses will be perfomed to search for DNA susceptibility loci and genes involved in the aetiology of orofacial clefts	—

Countries

Netherlands

Outcome results