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Characterization of functionality of HDL in patients with familial hypercholesterolemia

Characterization of functionality of HDL in patients with familial hypercholesterolemia - Functionality of HDL in FH patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON29851
Enrollment
36
Registered
2006-05-22
Start date
2006-10-10
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Diagnosis of Familial Hypercholesterolemia, age between 18 en 70 years, LDL-cholesterol level>200mg/dl, triglyceride-level

Exclusion criteria

Exclusion criteria: Type 2 diabetes mellitus, presence of inflammatory or infectious diseases, acute myocardial infarction or stroke during last six months, smoking, use of anti-inflammatory drugs (except aspirin) or anti-oxidant vitamins during last month

Design outcomes

Primary

MeasureTime frame
Compositional and structural properties of HDL subfractions as well as their protective activity towards LDL oxidation will be characterised.—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)