Evaluation of aortic elastic properties in the long-term follow-up of surgical and catheter interventional closure of the persistent ductus arteriosus

Evaluation of aortic elastic properties in the long-term follow-up of surgical and catheter interventional closure of the persistent ductus arteriosus - Aortic elastic properties after PDA closure

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON29770

Enrollment

Registered

2006-11-17

Start date

2006-01-10

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patent ductus arteriosus patent vessel between aorta and lung artery persistent ductus arteriosus

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Diagnosis of PDA or MARFAN, > 12 year

Exclusion criteria

Exclusion criteria: 1. Hemodynamically relevant residual cardiac anomalies 2. Genetic syndromes other than MARFAN 3. Contraindication against MRI-scanning (arrhythmias, pacemaker implantation, claustrophobia)

Design outcomes

Primary

Measure	Time frame
MRI-scanning: difference in aortic distensibility between patients and controls. Genetic testing: presence of a predisposing mutation known to be associated with inheritable aortic dissection and/or PDA.	—

Countries

Netherlands

Outcome results