The role of GPR161 and its modifiers in spina bifida: association studies in a human cohort.

The role of GPR161 and its modifiers in spina bifida: association studies in a human cohort. - UMCG SB

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON29737

Enrollment

1500

Registered

2006-09-12

Start date

2007-01-01

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cleft spine spina bifida

Interventions

None listed

Eligibility

Age

2 Years to 99 Years

Inclusion criteria

Inclusion criteria: All spina bifida patients and their biological parents registered at the spina bifida team Groningen will be asked to participate in the study. In addition, we will include new spina bifida patients born during the time of the study.

Exclusion criteria

Exclusion criteria: Patients with a known direct, iatrogenic cause for spina bifida (such as administration of anti-epileptic drugs during pregnancy) will be excluded from the study.

Design outcomes

Primary

Measure	Time frame
The allele frequencies of the candidate genes in spina bifida patients and their parents.	—

Secondary

Measure	Time frame
n.a.	—

Countries

Netherlands

Outcome results