allergy to cinnamon (-derivatives)
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients with a known cinnamon (-derivatives) allergy Patients with a positive fragrance patch test (fragrance mix 1 and/or fragrance mix 2) Age 18 years and above Written informed consent Skin to be tested has been clinical normal for the preceding two weeks
Exclusion criteria
Exclusion criteria: Pregnant women Topical therapy at skin to be tested in previous two weeks Lotions and commercial skin treatments on skin to be tested in less than 24 hours Previous (2 weeks) sun exposition at skin to be tested
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Regarding the literature we expect that concomitant reactions or cross-reactivity between cinnamon (-derivatives) and cinnamon-derived UV protectors will occur. If we detect this association between cinnamon-derivatives allergy and UV protectors, we expect the finding to be of important clinical relevance. | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency of allergy for cinnamon, cinnamon-derivatives and fragrance in the study population. Presence and/or absence of cross-reactivity and concomitancy among cinnamon(-derivatives) and cinnamon derived UV protectors. | — |
Countries
Netherlands