Visualization of the microcirculation of the nasal mucosa in vivo in different nasal disorders, using Sidestream Dark Field (SDF) imaging

Visualization of the microcirculation of the nasal mucosa in vivo in different nasal disorders, using Sidestream Dark Field (SDF) imaging - imaging of the nasal microcirculation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON29716

Enrollment

Registered

2006-08-11

Start date

2006-07-01

Completion date

Unknown

Last updated

2024-06-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

capillaries microcirculation

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Patients with active allergic rhinitis, idiopathic rhinitis, chronic rhinosinusitis or nasal polyps; - Males or females aged over 18 years with no maximum age; - Approval of the patient*s physician; - Written informed consent;

Exclusion criteria

Exclusion criteria: - Smoking; - Severe cardiac or pulmonary disorder; - Peripheral vascular disease; - Medication: systemic: * blockers, corticosteroids (local and systemic); any local nasal treatment; bronchodilatory inhalation medication for pulmonary diseases > 1000 *g/day; - Cystic fibrosis, Immotile cilia syndrome, Rendu-Osler-Weber disease, vasculitis; - Cocaine and/or alcohol abuse.

Design outcomes

Primary

Measure	Time frame
The following parameters will be used to asses the microcirculatory function in patients with allergic rhinitis, idiopathic rhinitis, chronic rhino sinusitis and nasal polyps: Flow in the capillary, venules and arterioles can be scored semi quantitatively or quantitatively: Semi quantitative scoring: (0 = no flow, 1 = intermittent flow, 2 = sluggish flow and 3 = continuous flow) Quantitative scoring: velocity, flow, diameter, length, density	—

Measure

Time frame

The following parameters will be used to asses the microcirculatory function in patients with allergic rhinitis, idiopathic rhinitis, chronic rhino sinusitis and nasal polyps: Flow in the capillary, venules and arterioles can be scored semi quantitatively or quantitatively: *Semi quantitative scoring: (0 = no flow, 1 = intermittent flow, 2 = sluggish flow and 3 = continuous flow) *Quantitative scoring: velocity, flow, diameter, length, density

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Secondary

Measure	Time frame
-	—

Countries

Netherlands

Outcome results