Assessment of cardio vascular risk by measurement of carotid intima-media thickness (cIMT) in adult type I Gaucher disease patients.

Assessment of cardio vascular risk by measurement of carotid intima-media thickness (cIMT) in adult type I Gaucher disease patients. - Intima media thickness in Gaucher type I disease.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON29706

Enrollment

140

Registered

2006-11-10

Start date

2006-09-01

Completion date

Unknown

Last updated

2024-05-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gaucher disease type I glucocerebrosidase deficiency

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: -Patients, older than 18 years, with proven GD I, as evidenced by decreased plasma glucocerebrosidase activity or genotyping. -Carriers, older than 18 years, with proven heterozygosity for the GD I genotype. -Controls, older than 18 years, with proven absence of the four most prevalent Gaucher-mutations, and, if related to a Gaucher patient, absence of the Gaucher mutations present in their family. -Patients, carriers and controls have to provide written informed consent to participate in the study.

Exclusion criteria

Exclusion criteria: none

Design outcomes

Primary

Measure	Time frame
cIMT	—

Secondary

Measure	Time frame
total cholesterol, LDL, HDL.	—

Countries

Netherlands

Outcome results