In the Netherlands approximately 500.000 children attend hospital emergency departments each year. Children with fever are responsible for about 50% of the paediatric emergency admissions (1). These children pose a diagnostic challenge at the paediatric emergency department (ED), since fever may have various causes, ranging from serious bacterial infections (e.g. meningitis, septicaemia, pneumonia, urinary tract infection) to self-limiting viral infections (2). Currently, these patients are ob
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 1 month - 16 years, visiting the paediatric emergency department of the ErasmusMC-Sophia with fever.
Exclusion criteria
Exclusion criteria: 1. Fever with a clear focus of only rhinitis or otitis; 2. Children with chronic morbidity, like: cystic fibrosis; broncho-pulmonary dysplasia; nephrotic syndrome and renal insufficiency; psychomotor retardation (Gross Motor Function Classification Scale IV and V); short bowel syndrome; malignancy currently in treatment regimen; immune deficiency, neutropenia; using immunosuppression medication; haemodynamic unstable heart disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient outcome: 1. Correct diagnosis (feverish children with serious bacterial infections); 2. False positive errors (children without the target diagnosis incorrectly exposed to diagnostic tests); 3. False negative errors (children with the target diagnosis incorrectly refrained from diagnostic tests). | — |
Secondary
| Measure | Time frame |
|---|---|
| Process outcome: 1. Patient's consultation time spent at the emergency department; 2. The number of diagnostic procedures (chest radiography, blood, urine and liquor tests and cultures); 3. Treatment procedures (antibiotic prescriptions), number of hospitalizations; 4. Follow up consultations within 1 week. Costs: Costs of diagnostic tests at the emergency department visit, initiated treatment, hospitalization, costs of missed diagnosis and their adverse events, costs of emergency care nurses and physicians. | — |
Contacts
P.O.box 2060