Depressie / Depression / Depressive disorder Dialyse / Dialysis / Renal replacement therapy Nierfalen / Eindstadium nierfalen / Kidney failure / End stage renal disease
Conditions
Interventions
Psychosocial intervention: Self-help cognitive based therapy, tailored for dialysis patients with build-in support from a psychotherapist. This treatment is based on a frequently used problem solving
Sponsors
OLVG Amsterdam
Eligibility
Inclusion criteria
Inclusion criteria: • ≥18 years of age • undergoing dialysis treatment for at least 90 days • being able to complete a questionnaire in Dutch • have a BDI depression score of 13 or higher (BDI = Beck Depression Inventory-II)
Exclusion criteria
Exclusion criteria: • Suicidal thoughts (measurend using a short screening survey) • Participation in other psychotherapeutic trials
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cluster randomized controlled trial of the intervention versus care as usual. The primary outcome is the depression score, measured using the Beck Depression Inventory (BDI). The difference between T0 and T1 (1-2 weeks after treatment) is the primary outcome for clinical effectiveness. Care as usual will be compared with the intervention group. | — |
Secondary
| Measure | Time frame |
|---|---|
| • BDI scores after 6, 12 and 18 months • Anxiety score, measured using the Beck Anxiety Inventory • Quality of life, measured using the SF-12 • Inflammatory markers, cortisol and tryptophan to explore possible pathophysiological mechanisms • Explore the effect on morbidity (hospital admissions) and mortality | — |
Contacts
Public ContactEls Nadort
OLVG-West hospital Amsterdam
Outcome results
None listed