depression in elderly depressie bij ouderen
Conditions
Interventions
Behavioural activation belongs to the third-generation behavioural treatments (Dimidjian & Davis 2009), and focuses at activating the patient to increase reward and at conceptualising ruminative think
Sponsors
Riagg Maastricht in collaboration with Maastricht University, University of Amsterdam & VU University Amsterdam
Eligibility
Inclusion criteria
Inclusion criteria: Inclusion criteria are 1) primary diagnosis of acute (i.e. started at least 12 months prior to referral) major and minor depression as assessed with the SCID-I; 2) a recurrent depressive episode is allowed; 3) a cut off score of 5/6 on the GDS-15 at screening (12); 4) age range 60-99; 5) can understand and speak the Dutch language; 6) willingness to participate in the study (signed informed consent).
Exclusion criteria
Exclusion criteria: Exclusion criteria are 1) psychotic features, psychotic disorder or bipolar disorder; 2) IQ<80 (clinical impression); 3) acute suicide risk; 4) substance dependence; 5) start of new medication within 3 months before start of the study (medication used for longer periods can be continued; stopping medication during the study is allowed); 6) medical condition that causes depression directly or through medication intake; 7) unstable medical condition; 8) MMSE score <20.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure will be the change in depression severity between respectively the intervention and exploration phase versus the baseline condition (Δ treatment effect). For the purpose of this study, we have chosen the GDS-15 as primary outcome measure, because Longwell and Truax (2005) warn for weekly administration of the BDI-II leading to decreasing scores merely as a result of the short re-administration period. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome measures are the BDI-II, the 17-item Hamilton Rating Scale for Depression (HRSD), patient acceptability of intervention (i.e. take up and drop out rates), medication use, patient attrition, happiness (one item question), and quality of life (EuroQol). We will apply the criteria for clinical response and remission as proposed by Dimidjian et al. (2006). They define response as a minimal 50% decline of symptoms compared to baseline, and remission is accomplished if the HRSD scores ≤ 7 and BDI ≤ 10. The SCID-I will be used to evaluate at pre- and post-treatment whether the major/minor depression is still present or in remission. | — |
Contacts
Public ContactM. Hanssen
Universiteitssingel 50
Outcome results
None listed