The present study focuses on the treatment of patients with borderline personality disorder.
Conditions
Interventions
-ST is based on an integrative cognitive model, combining cognitive behavior therapy with attachment theory, psychodynamic concepts, and experiential therapies (Jacob & Arntz, 2013). Central concepts
Sponsors
No external funding. This study is supported by the participating mental health institutes and the Department of Clinical Psychology, University of Amsterdam
Eligibility
Inclusion criteria
Inclusion criteria: - Borderline PD based on the DSM-5 as primary diagnosis (assessed with SCID-II or SCID-5-P) and a score of 20 or above on the Borderline Personality Disorder Severity index (BPDSI). - Age 18-65 - Ability to understand, read, write and speak Dutch.
Exclusion criteria
Exclusion criteria: - Alcohol or drug dependence needing clinical detox. (After 3 months of abstinence participation is possible). - Comorbid psychotic disorder (when > 1 year in full remission inclusion is possible). - Antisocial personality disorder with a history of physical interpersonal violence in the last two years. - DSM-5 Bipolar disorder, type 1 (current or past) . If there has been no manic episode the last year patients will be included. - Acute suicide risk - IQ < 80 - Schema Therapy of any kind (e.g., individual, group, inpatient, outpatient, day treatment) in the past year. - Patients should not start with any form of psychological treatment or medication during screening or during the study’s treatment or waitlist period. Medication should be on a stable level for 3 months, if not stopped. (Non-PD focused supportive treatment may be continued during wait and screening, but not during the study treatment and study 1-year follow-up period) - Not able to plan (group) therapy sessions of 90 minutes and individual sessions of 45-60 minutes once a week during 2 years within the treatment period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure is change in the severity and frequency of the DSM-5 BPD manifestations (BPDSI-IV, total score; Arntz et al., 2003; Giesen-Bloo, Wachters, Schouten, & Arntz, 2010). This outcome measure is frequently used in other studies of ST: Giesen-Bloo et al. (2006), Van Asselt et al. (2008), Nadort et al. (2009), and Wetzelaer et al. (2014). This interview yields dimensional total severity scores, as well as dimensional scores per criterion, and diagnostic status. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters 1. treatment dropout. The number of sessions and the date when treatment dropout took place will be monitored. 2. WAI-self report will be used for measuring patients’ thoughts and feelings about the working relation with the individual ST-therapist. 3. General functioning will be assessed with the WHODAS. This measure replaced the GAF, that was used in previous DSM editions, in the DSM-5. 4. Early Maladaptive Schemas will be assessed with the Dutch YSQ-3SF. (YSQ-3SF; Rijkeboer, 2012). The sum score of schemas the disconnection/ rejection domain will be used. 5. Severity of posttraumatic stress symptoms will be assessed with the post traumatic checklist for DSM-5 (PCL-5). (Weathers et al., 2013). 6. Quality of Life will be assessed with the EuroQol EQ-5D-5L (Herdman et al., 2011; Rabin & Charro, 2001). 7. Schema Modes will be assessed with the Schema Mode Inventory-2 (SMI-2; Bamelis et al., 2011), which assesses the frequency of Schema Mode activation for the modes relevant for the pertinent PDs. 8. General psychopathological symptoms as an index of severity of syndromal disorders will be assessed with the Brief Symptom Inventory (BSI; Derogatis & Melisaratos, 1983). 9. Happiness will be assessed with the 1-item happiness question validated in more than 30 countries (Veenhoven, 2011). 10. Medication and mental health care use will be monitored at each assessment. | — |
Contacts
Public ContactAnnemieke Koppeschaar
PsyQ Amsterdam
Outcome results
None listed