Intestinal Fatty Acid Binding Protein as a Marker for Increased Intra-Abdominal Pressure (I-Fabulous study)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON29639

Enrollment

200

Registered

2014-06-24

Start date

2011-04-18

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intra-abdominal hypertension and abdominal compartment syndrome

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with at least two risk factors as agreed by the World Society of the Abdominal Compartment Syndrome (WSACS) 2. Age 18 or older, with no upper age limit 3. Signed informed consent by patient or proxy

Exclusion criteria

Exclusion criteria: 1. Patients with bladder trauma or hematuria in whom intra-bladder pressure measurement is contra-indicated 2. Patients in whom intra-bladder pressure measurements are not possible due to intraperitoneal adhesions, bladder oppressive pelvic hematoma, abdominal packs in situ, or previous bladder removal 3. Patients with inflammatory bowel disease that may affect I-FABP levels, such as Crohn's disease or ulcerative colitis

Design outcomes

Primary

Measure	Time frame
Intestinal Fatty Acid Binding Protein (I-FABP) level in urine	—

Secondary

Measure	Time frame
Claudin-3 level in urine and serum I-FABP level in serum	—

Contacts

Public ContactO.J.F. Waes, van

Erasmus MC, Trauma Research Unit, dept. of Surgery Mailbox H-822k P.O. Box 2040, 3000 CA Rotterdam

o.vanwaes@erasmusmc.nl+31-10 7031050

Outcome results