Bronchopulmonary dyslasia
Conditions
Interventions
MRI
Sponsors
Erasmus MC- Sophia Children's Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Premature: born before 28 weeks PMA, good enough clinical condition to undergo MRI, parents manage Dutch language, informed consent by parents, at 34-40 weeks PMA: still admitted at the Sophia Children’s Hospital, severe BPD according to NHI criteria or at risk for severe BPD (received 28 days of oxygen therapy) Non- premature: born at a minimum of 37 weeks PMA, good enough clinical condition for MRI, parents manage Dutch language, informed consent by parents
Exclusion criteria
Exclusion criteria: Premature:contraindication for MRI investigation, congenital cardiovascular or pulmonary abnormalities (other than caused by prematurity) Non- premature:contraindication for MRI investigation, obtained mechanical ventilation, congenital cardiovascular or pulmonary abnormalities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The technical qualitative assessment of the MRIs | — |
Secondary
| Measure | Time frame |
|---|---|
| The ability of the MRI protocol to detect airway and lung ventilation, inflammation, perfusion and structural changes. Furthermore, the MRIs of prematurely born infants will be compared to the MRIs of non- premature patients without pulmonary disease. And lastly, the technical feasibility of MRI to detect cardiac structures will be assessed. | — |
Contacts
Public ContactBernadette Elders
Erasmus MC- Sophia Children's Hospital
Outcome results
None listed