1. Colorectal cancer (coloncarcinoom)
Conditions
Interventions
Both techniques (conventional colonoscopy and confocal endomicroscopy) are routinely used in clinical practice at the Department of Gastroenterology of our hospital. In this regard, patients participa
Sponsors
Dr. S. Sanduleanu, gastroenterologist
University Hospital Maastricht
Department of Gastroenterology and Hepatology
PO BOX 5800, 6202 AZ
Maastricht
e-mail: sda@sint.azm.nl
tel: 0031-43-3875021
Eligibility
Inclusion criteria
Inclusion criteria: 1. Clinical diagnostic criteria for either HNPCC (Amsterdam II criteria , Bethesda criteria or genetic criteria) or familial colorectal cancer type X – (1) CRC diagnosed age < 50 years; 2. at least 2 first-degree relatives with CRC regardless of age; 3. 1 first-degree and 1 second-degree relative with CRC regardless of age.
Exclusion criteria
Exclusion criteria: 1. Age < 18 years, presence of inflammatory bowel disease, or known polyposis syndromes; 2. Patients with incomplete endoscopic procedure due to anatomic or technique-related factors.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure will be the number of patients with at least one adenoma after conventional colonoscopy compared with the number of patients with at least one adenoma after pan-chromoendoscopy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcome measures assessing the diagnostic accuracy of combined pan-chromoendoscopy and confocal endomicroscopy are: total number of lesions detected; number of adenomas; number of advanced adenomas; number of flat lesions detected. | — |
Contacts
Public ContactS. Sanduleanu
University Hospital Maastricht Department of Gastroenterology and Hepatology PO BOX 5800
Outcome results
None listed